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Oral Sessions
Day 2, June 23（Mon.） 15:40-16:10
Room B (Maesato Center)
- 2B-O3-1540
Exploring Microdroplet Interactions in Electrospray-like Ion Sources
(NTHU)
oPawel Urban
Electrospray ionization (ESI) is widely recognized as one of the most effective methods for ion generation in mass spectrometry. We have conducted a series of studies to better understand the underlying processes that lead to ion formation. When using standard ESI electrolytes, we observed the occurrence of backward-moving droplets among the electrospray droplets, indicating that some droplets—produced in positive-mode electrospray—carry a negative charge. Most recently, we explored interactions between microdroplets and sample surfaces in desorption electrospray ionization (DESI), as well as interactions among droplets in extractive electrospray ionization (EESI). In DESI, charged droplets are propelled toward the sample surface due to the influence of a nebulizing gas. Some primary droplets interact directly with the surface, forming a liquid film without generating secondary droplets. In other cases, primary droplets splash upon impinging on the liquid film, creating liquid crowns and jets that give rise to secondary droplets. Some of these secondary droplets move toward the vacuum inlet, while others travel backward. In dual-emitter systems (e.g. EESI), most microdroplets in the spray and electrospray plumes appear not to involve in direct physical interaction. This observation suggests the need for alternative explanations for the processes occurring in dual-emitter systems.