The 10th Asia-Oceania Mass Spectrometry Conference (AOMSC2025) - organized by the Mass Spectrometry Society of Japan

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Poster Presentations

Day 2, June 23(Mon.) 

Room P (Maesato East, Foyer, Ocean Wing)

Cerebrospinal fluid metabolomics and lipidomics in autistic regression

(1UTS, 2NUS, 3USYD)
oJinni Yan1, Velda Han2, Russell Dale3

Within the landscape of neurodevelopmental disorders, autistic regression affects about 30% of children, however, the outcomes are detrimental, often leading to long-term neurodisability. Metabolomics has emerged as a promising tool in autism spectrum disorders to explore the pathophysiological mechanisms and reflect the interactions between genetic and environmental influences. Given the heterogeneity and neurologic manifestations of autistic regression, this represents an important area of research. This study presents an investigation of the CSF metabolomic profile in autistic regression.