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Poster Presentations
Day 2, June 23（Mon.）
Room P (Maesato East, Foyer, Ocean Wing)
- 2P-PM-49
Dual Ionization Ion Mobility Mass Spectrometry Hyphenated with Catalytic Oxygenation-Mediated Extraction
(NTHU)
oTzu-Ching Tsai, Maheswar Chamarthi, Pawel Urban
Corona discharge atmospheric pressure chemical ionization (APCI) is widely used for analyzing polar and mid-polar analytes with molecular weights below 1000 Da. In contrast, secondary electrospray ionization (SESI) is a soft ionization technique that effectively ionizes polar analytes. This study aims to integrate APCI and SESI with ion mobility-mass spectrometry (IM-MS) to analyze polar and mid-polar volatile organic compounds (VOCs) using both ionization sources, and to assess moisture-induced ion cluster formation. The coupling of a drift tube ion mobility spectrometer with a triple quadrupole mass spectrometer enables two-dimensional separation, facilitating compound identification based on reduced mobility (K<SUB>0) and mass-to-charge ratio (m/z). Catalytic oxygenation-mediated extraction (COME) is an environmentally friendly liquid-gas extraction technique that generates micro-oxygen bubbles via the catalytic decomposition of hydrogen peroxide. Here, this method is applied to extract VOCs from complex matrices such as spent cigarette filters and Taiwanese millet wine. The system operates automatically with a graphical user interface enabling real-time IM-MS data visualization. The dual-ionization COME-IM-MS system can provide two-dimensional data, enhancing the efficiency and accuracy of VOC analysis.