| Timetable |
| Download Conference Program |
| Download All Abstracts |
| Zoom Access |
| Corporate Program |
Oral Sessions
Day 4, June 25（Wed.） 11:40-11:55
Room A (Maesato West)
- 4A-O1-1140
Applications of Ion Mobility Mass Spectrometry in Metallosupramolecular Chemistry
(QUT)
oDavid Marshall, Michael Pfrunder, Jason Hong, Therese Fulloon, John Mcmurtrie, Stephen Blanksby, Kathleen Mullen
Self-assembled metallosupramolecular cages are discrete 3-dimensional complexes that have many potential applications in catalysis, sensing, and drug delivery. Complete characterisation of these coordination cages is challenging due to their dynamic behaviour, such as reversible guest binding, isomer exchange and structure interconversion. Moreover, NMR spectroscopy is limited to diamagnetic species and X-ray crystallography relies on the preparation of single crystals. Using several case studies, herein we demonstrate the utility of high-resolution ion mobility mass spectrometry to resolve and characterise individual coordination cages within dynamic mixtures, including bimetallic complexes, low-symmetry systems, and complexes containing paramagnetic metal ions such as Cu2+ or Ni2+.
By overcoming limitations associated with traditional characterisation methods, it is envisioned that advanced ion mobility-based analytical methods will encourage chemists to move beyond conventional design principles based on high-symmetry Platonic solids and embrace low-symmetry coordination cages containing a broader range of metal ions and ligands, significantly expanding the scope of accessible supramolecular architectures.