The 10th Asia-Oceania Mass Spectrometry Conference (AOMSC2025) - organized by the Mass Spectrometry Society of Japan

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Day 4, June 25(Wed.) 14:55-15:10

Room C (Top of Yaima)

  • 4C-O2-1455
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Standardization and Harmonization by the International Lipidomics Society

(LC Ltd)
oKim Ekroos

Mass spectrometry based lipidomics has revolutionized lipid research and led to a rapid increase in lipidomic data. However, numerous studies report poor lipidomics data quality due to misidentification and inaccurate quantification. We launched the Lipidomics Standards Initiative (LSI; https://lipidomics-standards-initiative.org/) in spring 2018 to address these challenges. Calling for the lipidomics community to work closer together towards standardization and harmonization and bringing lipidomics beyond current boarders, we established the International Lipidomics Society (ILS; https://lipidomicssociety.org) in 2019. As a result, we have developed community-based guidelines and minimum requirements for generating, reporting, and publishing lipidomic data. The Lipidomics Minimal Reporting Checklist has been established as a web-based questionnaire (https://lipidomicstandards.org/reporting_checklist/) to describe all essential steps of lipidomic experiments in a standardized way. These consensus guidelines foster data quality and provides a language for data comparison/exchange and advance lipidomics to a genuine analytical tool from basic research to clinical applications. In parallel, we have initiated several Interest Groups (https://lipidomicssociety.org/working-groups/) to actively harmonize and develop the field as a community with a close crosstalk to lipid biology, medicine, and beyond.