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Plenary Lectures Day1　Day2　Day3　Day4

MSSJ Award Lectures Day1

Oral Sessions Day2　Day3　Day4

Poster Presentations Day1　Day2　Day3　Day4

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Luncheon Seminars Day2　Day3　Day4

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Poster Presentations

Day 4, June 25（Wed.）　

Room P (Maesato East, Foyer, Ocean Wing)

• 4P-PM-46
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High resolution multi-turn TOF-MS for native mass analyses of large biomolecules

(¹Shimadzu Corporation, ²Osaka Metropolitan Univ., ³Yokohama City Univ.)
Yusuke Tateishi¹, Hiroko Morinaga¹, Hiroyuki Miura¹, Yoshinori Arita¹, ^oMasaru Nishiguchi¹, Daisuke Okumura¹, Hitomi Sawai², Michiko Tajiri³, Terukazu Nogi³, Satoko Akashi³

A high resolution multi-turn time-of-flight mass spectrometer (MT TOF-MS) has been developed for analysis of large biomolecules. A unique three-dimensional rotational flight path and next-generation high-sensitivity technology achieves mass resolving power of 200k for high m/z peaks. This new system is particularly useful for native mass spectrometry, as its high resolution in high m/z range provides new information which cannot obtained with conventional system. In this study, we demonstrate the advantages of high-resolution in native mass spectrometry through analyses of membrane proteins and other large biomolecules.

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