The Mass Spectrometry society of Japan - The 68th Annual Conference on Mass Spectrometry, Japan
Japanese

Abstract

Table of contents

Timetable

Plenary Lectures

Society Featured Lecture

Oral Sessions (Day1, Day2, Day3)

Poster Presentations (Day3)

Workshops

Lunchtime Seminars (Day1, Day2, Day3)

Oral Sessions

Day 1, May 19（Wed.）　15:30-15:50　Room C (Zoom)

1C-O3-1530　　PDF

Analysis of Synthetic Polymers in Electrospray Ionization-Ion Mobility Spectrometry-Tandem Mass Spectrometry with Fourier Transform Filter

(NITech)
oYuka Ozeki, Mizuki Omae, Shinya Kitagawa, Hajime Ohtani

Analyses of synthetic polymers in MS is effective for characterization of polymerization degree, backbone structure, and end groups. We recently developed the method to analyze the multiply charged (relatively large) synthetic polymers in electrospray ionization-ion mobility spectrometry-(tandem) mass spectrometry (ESI-IMS-MS(/MS)). However, the increase in the molecular weight of polymer decreases the ionization efficiency of the analytes in general. Thus, the identification of the most abundant peak from the isotopic peaks is often difficult due to noise. To solve this problem, we employed a noise-reduction method using Fourier transform filtering. The method was successfully applied to the identification of end groups of polymethylmethacrylates and characterization of co-polymers.