The Mass Spectrometry society of Japan - The 68th Annual Conference on Mass Spectrometry, Japan
Japanese

Abstract

Table of contents

Timetable

Plenary Lectures

Society Featured Lecture

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Day 3, May 21（Fri.）　　Room P1 (Zoom)

3P-16　　PDF

Analysis of steroids by metal-film surface-assisted laser desorption/ionization mass spectrometry

(1Toyama Pref. Univ., 2Kanazawa Univ.)
oTaichi Shimazaki1, Mai Yamakawa1, Shigehiro Karashima2, Issei Osaka1

Steroids could be detected sensitively by matrix-assisted laser desorption/ionization mass spectrometry (MALDI/MS) upon treatment with Girard’s reagents. In this study, we detect the steroids without derivatization reaction using surface-assisted laser desorption/ionization (SALDI) mass spectrometry with platinum film. Various steroids could be detected directly by the SALDI/MS. Additionally, the SALDI/MS allowed mass spectrometry imaging analysis of steroids on tissue section of animal adrenal glands with simple sample pretreatment.