Abstract

Poster Presentations

Day 3, May 21（Fri.）　　Room P2 (Zoom)

3P-46　　PDF

Mass Spectrometry Imaging identifies distinctive thymus-centric metabolic changes by Dexamethasone administration in mice

(¹Doshisha Univ., ²Shimadzu, ³Kansai Med. Univ., ⁴Kinki Univ.)
Yudai Tsuji¹, ^oHaruka Koyama¹, Shinichi Yamaguchi², Tomoyuki Nakamura³, Hiroyuki Shiono⁴, Masaya Ikegawa¹

Dexamethasone (Dex) is used for the treatment of severe inflammatory and immune-mediated diseases such as COVID-19 infection. In order to understand the metabolic effects of Dex on different organs, whole-body Mass spectrometry Imaging (MSI) was applied into murine model with a useful bioinformatics tool.