The Mass Spectrometry society of Japan - The 68th Annual Conference on Mass Spectrometry, Japan

Abstract

Poster Presentations

Day 3, May 21(Fri.)  Room P2 (Zoom)

OPIG DC Voltage Dependence of Proton Transfer Reaction of AngiotensinⅠ and AngiotensinⅡ

(Yokohama City Univ.)
oHiroto Ota

Biomolecules play an important role in biological phenomena in the living body. In other words, knowing the functions and structures of biomolecules is thought to be useful for elucidating biological phenomena. However, biomolecules interact with surrounding water molecules and other biomolecules in the living body, and it is very difficult to study original biomolecules. Therefore, in this study, biomolecules were placed in a vacuum to be an isolated state that did not interact with water molecules or other biomolecules. The peptides Angiotensin I and Angiotensin II were ionized using an electrospray ionization method, and proton transfer due to collision with Hexylamine was observed using a mass spectrometer. In this study, the OPIG DC dependence was investigated by changing the OPIG DC in the gas cell that induces the reaction.