Oral Sessions (Day1, Day2, Day3)
Poster Presentations
- Day 3, May 21（Fri.） Room P2 (Zoom)
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3P-55 PDF
Reaction temperature and OPIG-DC dependence of proton transfer reaction of Insulin 4+
It is important to study the properties of biomolecules that sustain life in order to understand biological phenomena. Biomolecules, such as proteins and peptides, maintain life by expressing various functions in vivo. Biomolecules express their functions by forming specific three-dimensional structures through hydrogen bonds and other interactions with the numerous water molecules in the cell. However, the three-dimensional structures of biomolecules are complex and often unresolved. In order to understand microscopically the complex structure formation of biomolecules, we studied the behavior of biomolecules in vacuum. In this study, we used electrospray ionization (ESI) to study the proton transfer reaction between a protein ion (Insulin) and a target molecule (1-Hexylamine). From the mass spectra, branching ratios and reaction rate constants were determined, and their reactivity and three-dimensional structures were discussed.