Abstract

Oral Sessions

Day 3, June 24（Fri.）　9:00-9:40　Room A (Main Hall)

3A-O1-0900　　PDF

Mass Spectrometry as an Aid to Elucidating Disease Mechanisms

(Shimadzu)
^oKoichi Tanaka

Mass spectrometry is able to measure an extremely wide variety of organic/inorganic compounds that can be pretreated, ionized, separated, detected, measured, and analyzed, and the recent development of new methods has made remarkable contributions to medicine and biochemistry in particular. However, the elucidation of the mechanisms of human pathophysiology, especially those related to the nervous system, is still in its early stages, and fully-fledged contributions to early detection and intervention are only just beginning to be realized. This talk will consider future prospects for elucidating neuropsychiatric disorders, using the ultra-early detection of the pathological change in Alzheimer's disease by MALDI-TOFMS as a concrete example, and the current progress being made in unraveling the complex mechanisms involved through integration with other methods, including medical instruments.