The Mass Spectrometry society of Japan - The 68th Annual Conference on Mass Spectrometry, Japan
Japanese

Abstract

Table of contents

Timetable

Plenary Lectures

Award Lecture

Oral Sessions (Day1, Day2, Day3)

Poster Presentations (Day1, Day2, Day3)

Panel Discussion

Luncheon Seminars (Day1, Day2, Day3)

Corporate Program

Oral Sessions

Day 3, June 24（Fri.）　10:20-10:40　Room A (Main Hall)

3A-O1-1020　　PDF

Impact of blood metabolome analysis in the field of mental health especially focused on depression and hikikomori

(1Kyushu Univ., 2Kyushu Univ.)
oTakahiro Kato1, Daiki Setoyama2, Toshio Matsushima1, Dongchon Kang2

Early intervention in mental disorders especially depression has been critical to prevent its negative impact including hikikomori and suicide. However, early intervention is difficult due to the lack of objective biological assessment systems for mental disorders. In real world clinical practice, some depressed patients tend to hide their depressive symptoms due to shame and/or stigma against mental disorders. Therefore, objective biological biomarkers should be developed to solve the above-difficult situations.
We have been conducting the blood metabolome analysis of patients with mental disorders such as depression and hikikomori. We have revealed that a variety of tryptophan-kynurenine and lipid related metabolites are involved in the pathophysiology of depression. In addition, we have shown several blood metabolites from patients with hikikomori. In this symposium, we will introduce our recent findings of metabolome data in mental disorders, and hope to discuss the future mental support system using blood metabolome data in psychiatry.