The Mass Spectrometry society of Japan - The 68th Annual Conference on Mass Spectrometry, Japan

Abstract

Oral Sessions

Day 3, June 24(Fri.) 9:20-9:40 Room C (411 and 412)

MetaboBank: repository of raw data and related resources for metabolome research

(1NIG, 2Kazusa DNA Res. Inst., 3Kyoto Univ., 4RIKEN, 5Kyoto Pref Univ., 6NAIST)
oToshiaki Tokimatsu1, Yuichi Kodama1, Asami Fukuda1, Takatomo Fujisawa1, Hideki Nagasaki2, Takeshi Ara2,3, Mikiko Takahashi4, Sachiko Ohsawa2, Norio Kobayashi4, Nozomu Sakurai1, Atsushi Fukushima4,5, Shigehiko Kanaya6, Hideki Hirakawa2, Masanori Arita1,4

MetaboBank is a database including primary repository for metabolome research and related secondary databases for metabolome research.
We launched the first version of MetaboBank repository in October 2020 at DNA Data Bank of Japan (DDBJ) Center. One year later, we have upgraded MetaboBank to version 2 to enhance integration with other biological resources by using standard metadata format with links to BioProject and BioSample records. The new metadata format is based on MAGE-TAB which has been used by functional genomics databases such as ArrayExpress of European Bioinformatics Institutes (EBI) and Genomic Expression Archive (GEA) of DDBJ Center. EBI’s metabolomics database MetaboLights has used ISA-TAB which is an abstracted model of MAGE-TAB. Recently, “SDRF-proteomics” has been developed based on MAGE-TAB as proteomics metadata format and used by EBI’s proteomics database PRIDE. The new MetaboBank MAGE-TAB format allows easier integration with these “omics” database using MAGE-TAB-based formats. The new MetaboBank data are linked with BioProject and BioSample records to realize integration with metabolomics data and related nucleotide sequencing data in INSDC. Public MetaboBank data are provided in Resource Description Framework (RDF) format in addition to MAGE-TAB for semantic integration with National Bioscience Database Center (NBDC) resources.