ポスター発表
- 第2日 6月23日(木) P会場(501,502,503)
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2P-30 PDF
MALDI および DESI 対応の 高分解能イメージングプラットフォーム
One key issue in imaging mass spectrometry (MSI) is analyte identification, particularly with regards to small molecules (metabolites/lipids). This is due to the abundance of molecular species with similar masses within a small mass range and no chromatographic separation. One way to improve compound identification confidence is through increased mass resolution and mass accuracy. To achieve this with a trapping style instrument requires a long scan duration. Here we demonstrate a multi reflecting-Time-of-Flight(ToF) instrument providing a mass resolution of up to 200,000 FWHM and a mass accuracy <500ppb with a scan speed of up to 10 Hz. The instrument supports both matrix assisted laser desorption ionization (MALDI) and desorption electrospray ionization (DESI) sources, specifically designed for imaging applications.