基盤セッション
第3日 6月12日（水） 9:15～9:33 D会場（中会議室202）
- 3D-O1-0915
タッピングモード走査型プローブエレクトロスプレーイオン化法によるヒト拡張型心筋症組織の質量分析イメージング
(1阪大院理・ 2阪大院理/FRC・ 3阪大院工・ 4阪大院医)
o大塚洋一1,2・ 新間秀一3・ 木岡秀隆4・ 大谷朋仁4・ 坂田泰史4
Mass spectrometry imaging of cardiac tissue donated by a patient with human dilated cardiomyopathy was performed using t-SPESI measurement system. Lipids localized in the fibrotic region and widely distributed in the myocardium were visualized. We found that the ion signal intensities of lipids presumed to be acylcarnitines were greatly decreased in cardiomyocytes near the fibrotic region.